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Systemic-onset juvenile idiopathic arthritis
1 OMIM reference -
2 associated genes
21 connected diseases
13 signs/symptoms
Disease Type of connection
Chuvash erythrocytosis
Von Hippel-Lindau disease
Familial exudative vitreoretinopathy
Adrenocortical carcinoma
B-cell chronic lymphocytic leukemia
Essential thrombocythemia
Familial pancreatic carcinoma
Giant cell glioblastoma
Gliosarcoma
Li-Fraumeni syndrome
Papilloma of choroid plexus
Precursor B-cell acute lymphoblastic leukemia
Acute promyelocytic leukemia
Autosomal dominant hypohidrotic ectodermal dysplasia
Cerebellar ataxia - hypogonadism
Dedifferentiated liposarcoma
Fibronectin glomerulopathy
Well-differentiated liposarcoma
Brachydactyly type E
Agenesis of the corpus callosum - intellectual deficit - coloboma - micrognathia
Familial isolated dilated cardiomyopathy
Synonym(s):
- Still disease
- Systemic polyarthritis
Classification (Orphanet):
- Rare respiratory disease
- Rare systemic or rheumatologic disease
Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: childhood
Average age of death: normal
Type of inheritance: unknown
External references:
1 OMIM reference -
No MeSH references
Gene symbol UniProt reference OMIM reference
IL6 P05231147620
MIF P14174153620
Very frequent
- Arthritis / synovitis / synovial proliferation
- Articular / joint pain / arthralgia
- Autoimmunity / autoimmune reaction / autoantibodies
- Biological inflammatory syndrome / increased erythrocyte sedimentation rate / CRP
- Cutaneous rash
- Fever / chilling
- Hydrarthrosis / articular / joint effusion

Frequent
- Mediastinal / hilar adenopathies

Occasional
- Abnormal pleura / hydrothorax / pleuresia / pleural effusion / chylothorax
- Acute abdominal pain / colic
- Hepatomegaly / liver enlargement (excluding storage disease)
- Pericardium anomalies / pericarditis / absence / cysts / pericardial effusion
- Splenomegaly